Phospho sulfonic acid (PSA) synthesized as an environmentally safe and efficient solid acid catalyst, and it used for the synthesis of several 2-disubstituted benzimidazoles, 2-substituted benzoxazoles, and 2-substituted quinoxalines in ethanol as a green solvent at ambient temperature is described. Chirality-Switchable Catalysts for Asymmetric Synthesis † Particular attention is focused on the exploration of new helical polymer scaffolds that are enantiomercally pure, structurally robust, and readily modifiable at their side chains. Therefore, the development of simple, rapid, and efficient procedures for the synthesis of quinoxaline derivatives is still needed. Novel rigid dendrimer containing cross-conjugated units are synthesized from the coupling of 2-thiophene-based dendron with 5,8-dibromo-2,3-dithienylquinoxaline. Ruiz and Juan C. V and Subba Narayana Kanchana Department of Chemistry, Sri Krishnadevaraya University, Anantapur, AP, India _____ ABSTRACT Quinoxaline derivatives have several pharmaceutical applications. European Chemical Bulletin, 2(4), 211-213. 1134/S1070363216120562. The procedure presented is operationally simple, practical and green. The direct conversion of α-hydroxy ketones and α-keto oximes into quinoxaline derivatives in the presence of a catalytic amount of ceric ammonium nitrate via metal-catalyzed aerobic oxidation followed by in situ trapping with aromatic 1,2-diamines in water as a green and efficient reaction media, is reported. Journal of the Electrochemical Society. Kathrotiya, Sagar P. "Monodisperse palladium nanoparticles supported on chemically derived graphene: An efficient nanocatalysts for the synthesis of quinoxaline and pyrido[3,2-b]pyrazine derivatives", 3. Dyes Pigments 71,245-250 (2006). Highly efficient and simple. Kiran Ga*, Laxminarayana Eb, Thirumala Chary Mc and Ravinder Ma. It has been found that compounds 4b, 8a and 8b were the most active compounds against the test organisms. Phospho sulfonic acid (PSA) synthesized as an environmentally safe and efficient solid acid catalyst, and it used for the synthesis of several 2-disubstituted benzimidazoles, 2-substituted benzoxazoles, and 2-substituted quinoxalines in ethanol as a green solvent at ambient temperature is described. N2 - Cupric sulfate pentahydrate is an efficient catalyst for a one-pot synthesis of quinoxaline derivatives. In addition, derivatives of carbazole and quinoxaline were employed to fabricate efficient solution-processed OLED devices. ir Abstract Efficient syntheses of quinoxalines from the reaction of a-hydroxy ketones and o- phenylenediamine in acetic acid via two methods, a thermal procedure. Efficient Synthesis of Quinoxaline Derivatives Catalyzed by p-Toluenesulfonic Acid Under Solvent-Free Conditions. , & Wang, Z. 2005 , 46 , 7183–7186. This protocol has several advantages such as high yield, good thermal stability, simple work up procedure, non‐toxic, clean, and. 35 In this article we report the synthesis of quinoxaline derivatives in the presence of IBX. Synthesis of some 3,4-dihydroquinazolinone-4-one, quinoxaline, benzoxazine, benzothiazine, pyran and pyrrolidinedione derivatives using readily available starting materials were described. Heravi et al has carried out the synthesis of quinoxalines and quinoxaline-2,3-diones as NMDA receptor antagonist in the presence of o-Iodoxybenzoic acid (IBX) at room temperature. - Serve as the point of contact for synthesis efforts across the Center. Synthesis and Characterization of 5,6 substituted, 2,3diaryl, Quinoxaline 1,4-di- N-Oxide derivatives and 7-substituted-2,3-diphenyl pyrido[3,2-b]pyrazine derivatives & Investigations of their Anticancer Activity beside Microbial. Naliapara* Department of Chemistry, Saurashtra University, Rajkot-360005, Gujarat, India *E-mail address: [email protected] V and Subba Narayana Kanchana Department of Chemistry, Sri Krishnadevaraya University, Anantapur, AP, India _____ ABSTRACT Quinoxaline derivatives have several pharmaceutical applications. Synthesis and Photovoltaic Properties of Quinoxaline-Based Semiconducting Polymers with Fluoro Atoms Tandem Solar Cells Made from Amorphous Silicon and Polymer Bulk Heterojunction Sub‐Cells Paper List. Read "An efficient synthesis of quinoxaline derivatives from 4-chloro-4-deoxy-α- d -galactose and their cytotoxic activities, Bioorganic & Medicinal Chemistry Letters" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. , & Wang, Z. Herein, we report that heteropoly acids are efficient catalysts for the synthesis of quinoxaline derivatives comparable with some other applied catalysts. An efficient, simple, and green procedure for the synthesis of quinoxaline derivatives is described. A literature search has revealed that synthesis of quinoxalines substituted with an indene moiety has not been described. Quinoxaline and its derivatives are an important class of benzoheterocycles displaying a broad spectrum of biological activities which have made them privileged structures in pharmacologically active compounds [2] , [3] , [4]. NH2 NH2 O O + EtOH. An efficient, simple and one-pot synthesis of pyrimidine derivatives by a three-component reaction of ketones, triethyl orthoformate, and ammonium acetate in the presence of boron sulfuric acid as. Author(s): Seyed Mohammad Vahdat, Saeed Baghery. Journal of the Electrochemical Society. Establish and maintain chemical and material inventories. The Chemistry of quinoxaline and spiro-indole derivatives has received considerable attention owing to their synthetic and biological importance. However, benzimidazole, like benzofuroxan, can also serve as an initial reagent in quinoxaline synthesis. In conclusion, we have developed a simple and efficient synthesis of quinoxaline derivatives (11 samples) using nano SbCl 5. The direct conversion of α-hydroxy ketones and α-keto oximes into quinoxaline derivatives in the presence of a catalytic amount of ceric ammonium nitrate via metal-catalyzed aerobic oxidation followed by in situ trapping with aromatic 1,2-diamines in water as a green and efficient reaction media, is reported. Journal of Industrial and Engineering Chemistry 2012 , 18 , 277-282. Efficient syntheses of quinoxalines from the reaction of α-hydroxy ketones and o- phenylenediamine in acetic acid via two methods, a thermal procedure and by microwave irradiation, are described. Several attempts have been undertaken in green chemistry to design synthetic methods in such a way that the starting materials are consumed to the maximum extent and waste products are minimum 1-20. A series of N-heterocyclic quinoxaline derivatives was successfully synthesized and applied as hole transport layers in quantum dot light-emitting diodes (QLEDs). A series of quinoxaline derivatives were efficiently synthesized in excellent yields by the reaction of 1,2-diamines and 1,2-diketones with grinding catalyzed by p-toluenesulfonic acid under solvent-free conditions at room temperature. Autino , 1 Nancy Quaranta , 2 Patricia G. reaction times, efficiency, generality, clean process, simple methodology, low cost, easy work-up, ease of preparation and regeneration of the catalyst and green conditions (in the synthesis of the quinoxaline derivatives) are advantages of the application of [Mesi]Cl as catalyst in the above organic reactions. An efficient protocol has been developed to access a series of novel highly complex bis-heterocyclic oxazepin-quinoxaline derivatives. Bhusareb and Rajendra P. The condensation of 1,2-diamines with 1,2-diketones using lithium bromide (LiBr) in H 2O/EtOH as a green reaction media at room temperature affords the title compounds in high to excellent yields and in short reaction times. Results and Discussion The required cyclization precursors 1, aryl substituted (1H-. An Efficient Green Synthesis of Quinoxaline Derivatives Using Carbon-Doped MoO 3-TiO 2 as a Heterogeneous Catalyst. 9% and luminance of 16760 cd m-2. A new efficient route for the formation of quinoxaline N-oxides and N,N'-dioxide using HOF. Quinoxaline derivatives are benzoheterocycles,. The new monomer 2,3,5,8-tetrathienylquinoxaline has been successfully synthesized with moderate yield over five steps. Novel rigid dendrimer containing cross-conjugated units are synthesized from the coupling of 2-thiophene-based dendron with 5,8-dibromo-2,3-dithienylquinoxaline. A green and efficient synthesis of quinoxaline derivatives catalyzed by 1- n -butyl-3-methylimmidazolium tetrafluoroborate The room temperature ionic liquid 1- n -butyl-3-methylimmidazolium tetrafluoroborate ([bmim]BF 4 ) was used to promote the synthesis of quinoxaline derivatives under grinding condition. A mild Hendrickson reagent-triggered intramolecular cascade cyclization, a highly enantioselective dihydroxylation, and an efficient palladium-catalyzed transformation of an O-allyl into N-allyl group are the key steps in the synthesis. AI2 was founded to conduct high-impact research and engineering in the field of artificial intelligence. A new efficient synthesis of 1α,25-dihydroxyvitamin D 3 LC-biotin is described, starting with readily available vitamin D 2 , and combining a classical approach to access 1α,25-dihydroxyvitamin D 3 , appropriate OH-protective group transformations, and a C-3-O-alkylation, suitable to connect the biotin-linker in a reliable, selective and high yielding strategy. Autino and Nancy Quaranta and Patricia G. Organic synthesis is a broad area that requires more efficient chemical methods and synthetic routes. Synthesis of Quinoxaline Derivatives using Sulfonic Acid Functionalized Imidazolium Salts as Highly Efficient and Reusable Bronsted Acidic Ionic Liquids Catalysts under Solvent-free Conditions SAMI SAJJADIFAR*, ESHAGH REZAEE NEZHAD and EHSAN KHOSRAVANI Department of Chemistry, Payame Noor University, P O Box 19395-4697, Tehran, Iran. title = "Development for an efficient synthesis method of 2'-deoxyguanosine-C8 adducts with several amino/nitro-arenes. Hexafluoroisopropanol (HFIP) is explored as an effective medium for the synthesis of quinoxaline derivatives in high yields at room temperature. Abstract: Efficient synthesis of quinoxaline derivatives from the reaction of ?-diketones and o-phenylenediamines in the presence of Keggin-type heteropolyacids (HPA) such as H3PMo12O40, H4SiW12O40, K7PMo2W9O40, H3PW12O40. An efficient total synthesis of (S)-14-azacamptothecin has been accomplished in 10 steps and 56% overall yield from 5H-pyrano[4,3-d]pyrimidine 8. Compared with the classical synthetic method, this new method. A tailor-made medium-band gap fluorinated quinoxaline-based conjugated polymer of PBDT-TFQ was designed and synthesized as a donor material for bulk-heterojunction (BHJ) solar cells. Welding Iron powder in the coating of welding electrode can significantly improve deposition efficiency. An efficient protocol for the synthesis of quinoxaline derivatives at room temperature using molecular iodine as the catalyst. Reaction between 1,2-phenylenediamine derivatives and arylidene malononitrile under aqueous media and also solvent-free conditions generates 2-aryl benzimidazole derivatives with a high yield. Quinoxaline derivatives are well known in the pharmaceutical industry and have been shown to possess a broad spectrum of biological activities. One-pot and efficient protocol for synthesis of quinoxaline derivatives Mohammad Reza Islami* and Zahra Hassani Department of Chemistry, Shahid Bahonar University, Kerman, Iran P. Synthesis, Characterisation And Biological Evaluation Of Some Novel Substituted Pyrazine And Quinoxaline,IJSR - International Journal of Scientific Research(IJSR), IJSR is a double reviewed monthly print journal that accepts research works. As part of current. A simple and efficient approach for the synthesis of thiophenyl thiazole based triazolo [4,3-a] quinoxaline derivatives is described. A simple, highly efficient and green procedure for the condensation of o-phenylenediamine with a-diketones in the presence of catalytic quantity of iodine. Efficient synthesis of novel 1,2,3-triazole-linked quinoxaline scaffold via copper-catalyzed click reactions† Ali Keivanloo ,* a Mohammad Bakherad , a Fateme Abbasi , a Tayebeh Besharati-Seidani a and Amir Hossein Amin a. synthesis of 1,5-benzodiazepine (4) and quinoxaline (5) washed with water (5 mL) and extracted with derivatives, we herein report an expeditious and efficient dichloromethane (10 mL). An efficient electrochemical method for the synthesis of quinoxaline-dione derivatives from oxidation of catechols in the presence of N 1, N 2-dibenzylethane-1,2-diamine. CH3CN was reported 23. The yields were ranged in 86. In addition, derivatives of carbazole and quinoxaline were employed to fabricate efficient solution-processed OLED devices. Journal of Industrial and Engineering Chemistry. 65 , 7129 (2009). The reaction of 1,2-diketone and 1,2-diaminobenzene derivative was carried out in water at room temperature using 10 mol% of task-specific dicationic. Phospho sulfonic acid (PSA) synthesized as an environmentally safe and efficient solid acid catalyst, and it used for the synthesis of several 2-disubstituted benzimidazoles, 2-substituted benzoxazoles, and 2-substituted quinoxalines in ethanol as a green solvent at ambient temperature is described. In summary, we have developed an efficient method for the synthesis of quinoxaline derivatives via the condensation of 1,2-diamines with α-diketones. Vázquez and Gustavo P. In the synthesis, the reaction of 1,2-phenylenediamines and phenacyl bromide were carried out using pyridine as a catalyst in THF at room temperature to give quinoxalines. AB - Cupric sulfate pentahydrate is an efficient catalyst for a one-pot synthesis of quinoxaline derivatives. It has been found that compounds 4b, 8a and 8b were the most active compounds against the test organisms. Substituted derivatives arise when α-ketonic acids, α-chlorketones, α- aldehyde alcohols and α-ketone alcohols are used in place of diketones. Herein, we report that heteropoly acids are efficient catalysts for the synthesis of quinoxaline derivatives comparable with some other applied catalysts. Romanelli 3 , *. ZnO-beta zeolite mediated simple and efficient method for the one-pot synthesis of quinoxaline derivatives at room temperature; Determination of ultra-trace amounts of inorganic selenium species in natural water by ion chromatography-inductively coupled plasma-mass spectrometry coupled with nano-Al2O3 solid phase extraction. JAGANNADHAM and SUMANGALA RAO Research Centre, Department of Chemistry Chaitanya PG College, Warangal-506 001, India [email protected] EFFICIENT CATALYST FOR THE SYNTHESIS OF QUINOXALINE DERIVATIVES IN TAP-WATER UNDER SONICATION Anshu Dandia,[a]* Ruby Singh,[a] Jyoti Joshi[b] and Shuchi Maheshwari[b] Keywords: Magnetically separable nanoparticles, quinoxaline derivatives, one-pot synthesis, ultrasound irradiation. Quinoxaline derivatives have been prepared in good to excellent yields using silica gel as catalyst from various 1,2-diketones and 1,2-diamines under solvent-free conditions for the first time. An Efficient Synthesis of Thiazolo and Thiadiazolo Quinoxaline Derivatives in Ionic Liquid B. Compared with the classical synthetic method, this new method. 2005 , 46 , 7183–7186. Page 280 One-pot and efficient protocol for synthesis of quinoxaline derivatives Mohammad Reza Islami* and Zahra Hassani Department of Chemistry, Shahid Bahonar University, Kerman, Iran P. An Alternative Approach to the Synthesis of New Pyrimido[5′,4′:5,6][1,4] Thiazino[2,3-B]Quinoxaline Derivatives Mehdi Bakavoli, Hosein Eshghi, Hamid Azizollahi, Sattar Saberi, and Marziyeh Akbarzadeh. This permits the subsequent condensation with another molecule of Benzaldehyde in benzoin synthesis and loss of the. Herein, we report that heteropoly acids are efficient catalysts for the synthesis of quinoxaline derivatives comparable with some other applied catalysts. High yields, relatively short reaction times, efficiency, generality, clean process, simple methodology, low cost, easy work-up, ease of preparation and regeneration of the catalyst and green conditions (in the synthesis of the quinoxaline derivatives) are advantages of the application of [Mesi]Cl as catalyst in the above organic reactions. The condensation of 1,2-diamines with 1,2-diketones using lithium bromide (LiBr) in H 2O/EtOH as a green reaction media at room temperature affords the title compounds in high to excellent yields and in short reaction times. Proof corrected by the author Available online since samedi 12 janvier 2013 - Rice husk: A mild, efficient, green and recyclable catalyst for the synthesis of 12-Aryl-8, 9, 10, 12-tetrahydro [a] xanthene-11-ones and quinoxaline derivatives - EM|consulte. The procedure presented is operationally simple, practical and green. V and Subba Narayana Kanchana Department of Chemistry, Sri Krishnadevaraya University, Anantapur, AP, India _____ ABSTRACT Quinoxaline derivatives have several pharmaceutical applications. Quinoxaline derivatives are well known in the pharmaceutical industry and have. The objective of present research work is to provide green technique for synthesis of quinoxaline derivative. organic synthesis, and we present an efficient and practical protocol, which rapidly synthesized 5,6-dihydroindolo[1,2-a]quinoxaline derivatives by copper-catalyzed intramolecular N-arylation with good to excellent yields. Autino , 1 Nancy Quaranta , 2 Patricia G. Highly efficient and simple methods have been described for the synthesis with excellent yields (95-98%). ZnO-beta zeolite mediated simple and efficient method for the one-pot synthesis of quinoxaline derivatives at room temperature; Determination of ultra-trace amounts of inorganic selenium species in natural water by ion chromatography-inductively coupled plasma-mass spectrometry coupled with nano-Al2O3 solid phase extraction. Conjugated copolymers based on benzodithiophene (BDT) derivatives and thiophene‐quinoxaline‐thiophene (TQT) segments represent an efficient class of light harvesting materials for organic photovoltaic (OPV) applications. Hexafluoroisopropanol (HFIP) is explored as an effective medium for the synthesis of quinoxaline derivatives in high yields at room temperature. The one-pot cascade process involves the acidic elimination of α-aminoxylated dicarbonyl compounds to generate 1,2,3-tricarbonyl compounds and subsequent condensation with 1,4-N,N or -N,O dinucleophiles to afford quinoxaline, pyrazine. The hypothesis of quantization level. Synthesis of bis-quinoxaline derivatives using Tonsil clay as a catalyst A convenient and efficient synthesis of new bis -quinoxaline is described, involving condensation of 1,2-diamines with 9-ethyl-3,6-di(1,2-dioxoethyl)carbazole in the presence of Tonsil clay, a readily available and inexpensive catalyst. The room temperature ionic liquid 1-n-butyl-3-methylimmidazolium tetrafluoroborate ([bmim]BF4) was used to promote the synthesis of quinoxaline derivatives under grinding condition. Russian Journal of General Chemistry 2016, 86 (12) , 2887-2890. They have been screened for their antibacterial. Furthermore, the quinoxaline ring is a core structure of several drug molecules and acceptors such as clofazimine, echinomycin and actinomycin [14-17]. A tailor-made medium-band gap fluorinated quinoxaline-based conjugated polymer of PBDT-TFQ was designed and synthesized as a donor material for bulk-heterojunction (BHJ) solar cells. of Management Efficiency Ekaterina A. Therefore, the development of simple, rapid, and efficient procedures for the synthesis of quinoxaline derivatives is still needed. title = "Development for an efficient synthesis method of 2'-deoxyguanosine-C8 adducts with several amino/nitro-arenes. Huang et al found Keggin type heteropolyacids to be an efficient and reusable catalyst for the synthesis of biologically active quinoxaline derivatives from the condensation of 1,2-diamine with 1,2-dicarbonyl. A convenient synthesis of substituted quinoxalines in good yields from o-phenylenediamines and ynones via Michael addition, dehydration condensation, and base-promoted C-α-CH 2-extrusion under metal-free conditions features high regioselectivity, efficiency, and environmental friendliness. Romanelli and La Plata Baan}, title = {The cientificWorldJOURNAL Research Article An Efficient Protocol for the Synthesis of Quinoxaline Derivatives at Room Temperature Using Recyclable}, year = {2011}}. JAGANNADHAM and SUMANGALA RAO Research Centre, Department of Chemistry Chaitanya PG College, Warangal-506 001, India [email protected] Synthesis and Solution Properties of a Rigid Helical Star Polymer: Three-Arm Star Poly(quinoxaline-2,3-diyl) Hirokazu Hasegawa, Yuuya Nagata, Ken Terao, and Michinori Suginome Macromolecules , 2017 , 50 , 7491-7497, 10. Crossref, CAS, Google Scholar; 12 Sakata G, Makino K, Karasawa Y. Previously unknown tritium labeled N-phenyl quaternary derivatives of pyrazine and quinoxaline, which are potential radioactive biomarkers, have been obtained by nuclear-chemical method. As part of current. Derivatives of quinoxaline prepared from cinnamils NH2 A NH2 B O HO O HO RT N H H A N B O O + Grinding Scheme 3 One-pot efficient green synthesis for derivatives of quinoxaline Quinoxaline derivative metal complexes: Spectrophotometric study of Co(II) and Ni(II) complexes with quinoxaline-2,3-dithiol has been reported by Ayres et al 23. The reaction can be performing in water as well as ethanol. A novel and efficient method for the synthesis of quinoxaline derivatives has been developed. Huang et al found Keggin type heteropolyacids to be an efficient and reusable catalyst for the synthesis of biologically active quinoxaline derivatives from the condensation of 1,2-diamine with 1,2-dicarbonyl. Construction of a novel quinoxaline as a new class of Nrf2 activator Chemistry Central Journal , Sep 2019 Murugesh Kandasamy , Kit-Kay Mak , Thangaraj Devadoss , Punniyakoti Veeraveedu Thanikachalam , Raghavendra Sakirolla , Hira Choudhury , Mallikarjuna Rao Pichika. Synthesis and properties of new dialkoxyphenylene quinoxaline‐based donor‐acceptor conjugated polymers and their applications on thin film transistors and solar cells Journal of Polymer. Present synthesis complies with principle of Green chemistry. In conclusion, we have developed a simple and efficient synthesis of quinoxaline derivatives (11 samples) using nano SbCl 5. Conclusion In summary, TiO 2 nanoparticles with diameter of 50 nm was successfully synthesized via sol-gel method and used as eco-friendly (non-toxic, recyclable), easily available, inex-pensive and efficient homogeneous catalyst for the synthesis of quinoxaline derivatives in high to excellent yields with. An efficient protocol has been developed to access a series of novel highly complex bis-heterocyclic oxazepin-quinoxaline derivatives. An efficient synthesis of the potential pharmacophore 1,4 -dihydro -quinoxaline -2,3 -dione (1) has been achieved in a one-pot reaction at room temperature from substituted o-phenylene diamine and oxalic acid under solvent -free conditions by a simple grinding method with unsurpassed atom economy. Efficient and one-pot synthesis of 1,8-dioxo-octahydroxanthenes was described by Knoevenagel condensation, Michael addition and cyclodehydration of dimedone. Easily synthesized1-methyl-3- (2-oxyethyl) -1H-imidazol-3-ium-borate sulfonic acid {[MOEI] -BSA} as a novel catalyst efficiently promoted the synthesis of quinoxaline derivatives via condensation of various diamines with 1, 2-dicarbonyl compounds at room temperature conditions in ethanol. The one-pot cascade process involves the Highly efficient synthesis of quinoxaline derivatives from 1,2-benzenediamine and [equation]-aminoxylated 1,3-dicarbonyl compounds | SpringerLink. organic synthesis, and we present an efficient and practical protocol, which rapidly synthesized 5,6-dihydroindolo[1,2-a]quinoxaline derivatives by copper-catalyzed intramolecular N-arylation with good to excellent yields. Example of contrast and compare essay. Bhusareb and Rajendra P. A fast, high efficiency and environmentally friendly procedure for the synthesis of 2-aryl benzim-idazole derivatives has been reported. Crossref, CAS, Google Scholar; 12 Sakata G, Makino K, Karasawa Y. PRASANNA*, B. Sulfonic acid functionalized SBA-15 (SBA-Pr-SO3H) with pore size 6 nm was proved to be an efficient heterogeneous nanoporous solid acid catalyst in the synthesis of quinoxaline derivatives from the reaction of o-Phenylenediamines with 1, 2-diketone compounds in very good yields. SO3H-functionalized metal organic frameworks: an efficient heterogeneous catalyst for the synthesis of quinoxaline and derivatives RADOELIZO S. Welding Iron powder in the coating of welding electrode can significantly improve deposition efficiency. Journal of Industrial and Engineering Chemistry. As part of our ongoing research on the development of alternative synthetic procedures for the synthesis of biologically active heterocyclic compounds and the use of green chemistry techniques in organic synthesis, herein we report a simple and efficient method for the preparation of quinoxaline derivatives using heteropolyacids HPMo 11 VFeO 40. Box 76169-133 E-mail: [email protected] 85 · DOI : 10. quinoxaline 1,4-di-N-oxide derivatives. An efficient, simple, and green procedure for the synthesis of quinoxaline derivatives is described. 催化学报, 2015, 36(8): 1379-1386. AB - Cupric sulfate pentahydrate is an efficient catalyst for a one-pot synthesis of quinoxaline derivatives. Recently, we have also reported some quinoxaline-based colorimetric and ratiometric sensors for specific detection of nickel cations [18-20]. The catalyst was shown to be equally effective for the synthesis of quinoxalines from o -phenylenediamine and α-bromo ketones under the similar reaction conditions. 1 Quinoxaline and its derivatives are very important in various fields of science like chemical, pharmaceutical and material industries. EFFICIENT CATALYST FOR THE SYNTHESIS OF QUINOXALINE DERIVATIVES IN TAP-WATER UNDER SONICATION Anshu Dandia,[a]* Ruby Singh,[a] Jyoti Joshi[b] and Shuchi Maheshwari[b] Keywords: Magnetically separable nanoparticles, quinoxaline derivatives, one-pot synthesis, ultrasound irradiation. Synthesis and Photovoltaic Properties of Quinoxaline-Based Semiconducting Polymers with Fluoro Atoms Tandem Solar Cells Made from Amorphous Silicon and Polymer Bulk Heterojunction Sub‐Cells Paper List. Isopropylidenation of 4-chloro-4-deoxy-α-d-galactose with 2,2-dimethoxypropane, followed by selective hydrolysis, afforded 2,3-O-isopropylidene-4-chloro-4-deoxy-d-galactose di-methyl acetal (3) as a sole product. This permits the subsequent condensation with another molecule of Benzaldehyde in benzoin synthesis and loss of the. Helio sequence negotiations review journal newspaper. INTRODUCTION:In recent years, the most important goal of synthetic chemists is the development of resource-efficient and sustainable chemical methodologies. Sulfonic acid functionalized SBA-15 (SBA-Pr-SO 3 H) with pore size 6 nm was proved to be an efficient heterogeneous nanoporous solid acid catalyst in the synthesis of quinoxaline derivatives from the reaction of o -Phenylenediamines with 1, 2-diketone compounds in very good yields. A series of quinoxaline derivatives were efficiently synthesized in excellent yields by the reaction of 1,2-diamines and 1,2-diketones with grinding catalyzed by p-toluenesulfonic acid under solvent-free conditions at room temperature. ensuring the comfort of living is the income level of the population. Synthesis and properties of new dialkoxyphenylene quinoxaline‐based donor‐acceptor conjugated polymers and their applications on thin film transistors and solar cells Journal of Polymer. Additionally, room temperature and microwave-irradiation solvent-free synthesis was more efficient than a. Vázquez , 3 and Gustavo P. An Efficient Synthesis of Thiazolo and Thiadiazolo Quinoxaline Derivatives in Ionic Liquid B. 22034/chemm. Nov 07, 2002 · Highly efficient synthesis of quinoxaline derivatives catalized by iridium complex. Semantic Scholar is a project at the Allen Institute for AI (AI2). Montmorillonite K-10: An efficient and reusable catalyst for the synthesis of quinoxaline derivatives in water. Synthesis and Biological Activity of Azine Heterocycle Functionalized Quaternary Phosphonium salts Patil Akshay Ravindra and S Karpagam Department of Chemistry, School of Advanced Sciences, VIT University, Vellore. Tetrahedron Lett. Huang et al found Keggin type heteropolyacids to be an efficient and reusable catalyst for the synthesis of biologically active quinoxaline derivatives from the condensation of 1,2-diamine with 1,2-dicarbonyl. , 1985 , 1987 , 1990 , 1998 , 1999) are produced with heterocyclic groups in their main chain by addition of quinoxaline cycle into the polymer main chain and reaction of quinoxaline hydroxyl compound with diacids and quinoxaline amine compound with. Legend of the five rings review journal newspaper. Babita Tanwar, Asim Kumar, Perumal Yogeeswari, Dharmarajan Sriram, Asit K. By inducing sp 2 N-atoms into the quinoxaline backbone, the electron affinity of the obtained material was enhanced, and its optical properties and bandgap became tunable. Efficient syntheses of quinoxalines from the reaction of α-hydroxy ketones and o- phenylenediamine in acetic acid via two methods, a thermal procedure and by microwave irradiation, are described. Polyester with quinoxaline ring in the main chain This type of polyesters ( Akutsu et al. Heterocycles 27,2481-2515 (1988). The aim of this work was to investigate a new series of chalcones containing a quinoxaline unit as B-ring, and to compare the quinoxaline efficiency to other bicyclic B-rings such as a 2-naphthyl or 3,4-methylenedioxy-phenyl unit as inhibitors of ABCG2. Quinoxaline as a potent heterocyclic‌. Using this method, quinoxaline derivatives as biologically interesting compounds are produced in high to excellent yields and short reaction times. A novel and efficient method for the synthesis of quinoxaline derivatives has been developed. Jan 21, 2016 · Introduction. Journal of Physical Chemistry C , 113 (4), 1589-1595. SRINIVAS, Y. [58] Jaso, A. Adapa* RJC, 1(1), 188-194, 2008. A novel and efficient method for the synthesis of quinoxaline derivatives has been developed. The reaction can be performing in water as well as ethanol. This polymer is possessed of an intrachain donor–acceptor architecture and exhibits a broad and strong absorption spectrum across the entire UV–vis region. An efficient and inexpensive sulfated polyborate catalyst was applied for the rapid synthesis of quinoxaline derivatives from various substituted o-phenylenediamines and 1,2-diketones/ α-hydroxy. Box 76169-133 E-mail: [email protected] Therefore, the development of simple, rapid, and efficient procedures for the synthesis of quinoxaline derivatives is still needed. com Received 21 July 2011; Accepted 5 September 2011. The method is very convenient and applicable for alkyl as well as aryl amines and phenacyl bromides. The procedure presented is operationally simple, practical and green. High yields, relatively short reaction times, efficiency, generality, clean process, simple methodology, low cost, easy work-up, ease of preparation and regeneration of the catalyst and green conditions (in the synthesis of the quinoxaline derivatives) are advantages of the application of [Mesi]Cl as catalyst in the above organic reactions. The combined organic extracts method for the synthesis of 1,5-benzodiazepine were dried over anhydrous Na SO , concentrated in. Huang et al found Keggin type heteropolyacids to be an efficient and reusable catalyst for the synthesis of biologically active quinoxaline derivatives from the condensation of 1,2-diamine with 1,2-dicarbonyl. The condensation of 1,2-diamines with 1,2-diketones using lithium bromide (LiBr) in H 2O/EtOH as a green reaction media at room temperature affords the title compounds in high to excellent yields and in short reaction times. An efficient total synthesis of (S)-14-azacamptothecin has been accomplished in 10 steps and 56% overall yield from 5H-pyrano[4,3-d]pyrimidine 8. have investigated the synthesis of quinoxalines in the presence of heteropoly acid at room temperature. Using this method, quinoxaline derivatives as biologically interesting compounds are produced in high to excellent yields and short reaction times. Thiamine hydrochloride catalyst for one-pot synthesis of quinoxaline derivatives at ambient temperature 163 carbonyl oxygen atom of 1,2-diketone, thereby increas-ing the polarization and promoting the cyclocondensa-tion reaction. effective, economical nature, easy to handle and it is a step toward green synthesis [3]-[5]. Jan 21, 2016 · Introduction. Our research toward the expansion of efficient and environmentally benign synthetis methodologies using eco-friendly conditions[30], we report here the synthesis of quinoxalines from o-phenylenediamine and various α-diketones in the presence. ir Abstract Efficient syntheses of quinoxalines from the reaction of a-hydroxy ketones and o- phenylenediamine in acetic acid via two methods, a thermal procedure. An Efficient and Recyclable Nanoparticle-Supported Cobalt Catalyst for Quinoxaline Synthesis. The reaction of 1,2-. Proof corrected by the author Available online since samedi 12 janvier 2013 - Rice husk: A mild, efficient, green and recyclable catalyst for the synthesis of 12-Aryl-8, 9, 10, 12-tetrahydro [a] xanthene-11-ones and quinoxaline derivatives - EM|consulte. Quinoxaline derivatives have been prepared in good to excellent yields using silica gel as catalyst from various 1,2-diketones and 1,2-diamines under solvent-free conditions for the first time. Although there are many reports on the synthesis of quinoxaline derivatives, most of them suffer from narrow scope of substrates, harsh reaction conditions, and tedious work-up procedures. Heterogenized tungsten complex: an efficient and high yielding catalyst for the synthesis of structurally diverse tetra substituted pyrrole derivatives via four-component assembly AB Atar, YT Jeong Tetrahedron Letters 54 (41), 5624-5628 , 2013. Quinoxaline derivatives are well known in the pharmaceutical industry and have. The rearrangement represents a facile approach to medicinally important biheterocyclic compounds. of Management Efficiency Ekaterina A. Sulfonic acid functionalized SBA-15 (SBA-Pr-SO 3 H) with pore size 6 nm was proved to be an efficient heterogeneous nanoporous solid acid catalyst in the synthesis of quinoxaline derivatives from the reaction of o -Phenylenediamines with 1, 2-diketone compounds in very good yields. Sarda,a Suresh S. Bentonite clay K-10 acts as an efficient reagent for the preparation of quinoxaline derivatives via the condensation of aryl and alkyl 1,2-diamines with α-diketones in ethyl alcohol as a green media at room temperature. Compound 2 on treating with quinoxaline-2-car. An efficient protocol has been developed to access a series of novel highly complex bis-heterocyclic oxazepin-quinoxaline derivatives. The procedure presented is operationally simple, practical and green. Author(s): Seyed Mohammad Vahdat, Saeed Baghery. Our research toward the expansion of efficient and environmentally benign synthetis methodologies using eco-friendly conditions[30], we report here the synthesis of quinoxalines from o-phenylenediamine and various α-diketones in the presence. Phospho sulfonic acid (PSA) synthesized as an environmentally safe and efficient solid acid catalyst, and it used for the synthesis of several 2-disubstituted benzimidazoles, 2-substituted benzoxazoles, and 2-substituted quinoxalines in ethanol as a green solvent at ambient temperature is described. For antiseptic substance in food packing and reducing agent. Ceria and Modified Ceria: A Reusable Catalyst for the Green Synthesis of 2,3-diphenyl Quinoxaline at Room Temperature Simple, highly versatile and efficient synthesis of 2,3-diphenylquinoxalines is achieved from benzil and o-phenylene diamine using ceria and modified ceria as the catalyst. 2-Mercapto-6-phenylpyrimidin-4-ol1, on reaction with POCl3 to afford 2,4-dichloro-6- phenylpyrimidine 2. The objective of present research work is to provide green technique for synthesis of quinoxaline derivative. An alternating polyfluorene copolymer based on fluorene donor and quinoxaline acceptor (P1) and an alternating terpolymer (P2) with fluorene (50 %) donor and quinoxaline (25 %) and benzothiadiazole (25 %) acceptor units were designed and synthesized for use as photoactive materials in solar cells. Synthesis and antimicrobial activity of some new quinoxaline derivatives Subba Rami Reddy SR*, Suryanarayana Rao. 2005 , 46 , 7183–7186. coli as expression system • Learning techniques on vector design (for synthesis and secretion of chemicals), protein co-expression system. Efficient synthesis of a collection (combinatorial library) of structurally diverse and complex small molecules that differ in stereochemistry, functional groups and molecular framework. The new monomer 2,3,5,8-tetrathienylquinoxaline has been successfully synthesized with moderate yield over five steps. The combined organic extracts method for the synthesis of 1,5-benzodiazepine were dried over anhydrous Na SO , concentrated in. مشخصات نویسندگان مقاله ZnO nanoparticles: An Efficient Nanocatalyst for the synthesis of quinoxaline in solvent Free Condition B Sadeghi - Department of Chemistry, Islamic Azad University, Yazd Branch. photosensitizers to broaden the active area of diaryliodonium salts. 9% and luminance of 16760 cd m-2. 85 · DOI : 10. Derivatives of quinoxaline prepared from cinnamils NH2 A NH2 B O HO O HO RT N H H A N B O O + Grinding Scheme 3 One-pot efficient green synthesis for derivatives of quinoxaline Quinoxaline derivative metal complexes: Spectrophotometric study of Co(II) and Ni(II) complexes with quinoxaline-2,3-dithiol has been reported by Ayres et al 23. In continuation of our interest on the development of efficient, practical and eco-friendly procedures for the synthesis of condensed benzo[N,N]-heterocyclic compounds, 33-35 we herein wish to introduce NH 4 Cl-CH 3 OH as a mild and effective catalyst system for the synthesis of quinoxaline derivatives. Russian Journal of General Chemistry 2016, 86 (12) , 2887-2890. : Facile Method of Quinoxaline Synthesis Using Phenol as a 98 New, Efficient and Cheap Catalyst at Room Temperature. In addition, derivatives of carbazole and quinoxaline were employed to fabricate efficient solution-processed OLED devices. Substituted derivatives arise when α-ketonic acids, α-chlorketones, α- aldehyde alcohols and α-ketone alcohols are used in place of diketones. 15, and 298. 1 was believed to be a potential template for the synthesis of novel class of bioactive compounds. Huang et al found Keggin type heteropolyacids to be an efficient and reusable catalyst for the synthesis of biologically active quinoxaline. Both 1,5-benzodiazepine and quinoxaline derivatives are important heterocycles in pharmaceuticals. Provided is a mixture which can be subjected to a Diels-Alder reaction, comprising polymer (I) and polymer (II), wherein the structures of the polymer (I) and the polymer (II) are as shown in (I), wherein x1, y1, x2, y2, z1 and z2 are percentage molar contents; said x1 is >0, x2 is >0, y1 is >0, y2 is >0, z1 is ≥0, and z2 is ≥0; x1+y1+z1, and x2+y2+z2=1; Ar1, Ar2, Ar2-1, Ar3. a simple and efficient microwave-assisted synthesis of quinoxaline and spiro-indole derivatives in xylene Shivam Bajpai 1 , Sundaram Singh 2 and Vandana srivastava 3 Research Scholar, Department of Chemistry, IIT-BHU, Varanasi, India. Comptes Rendus Chimie - In Press. Nickel hydrazine perchlorate synthesis meaning. Iranian Journal of Chemistry and Chemical Engineering (IJCCE) , 32, 3, 2013, 61-67. Isopropylidenation of 4-chloro-4-deoxy-α-d-galactose with 2,2-dimethoxypropane, followed by selective hydrolysis, afforded 2,3-O-isopropylidene-4-chloro-4-deoxy-d-galactose di-methyl acetal (3) as a sole product. quinoxaline-2-one and its derivatives can be found in summary reviews of the quinoxaline chemistry7 Numerous methods are available for the synthesis of quinoxaline derivatives which Extensive researches have generated numerous synthetic approaches for the construction of the skeleton of such heterocycles. Efficient and one-pot synthesis of 1,8-dioxo-octahydroxanthenes was described by Knoevenagel condensation, Michael addition and cyclodehydration of dimedone. Alfa Aesar is a leading manufacturer and supplier of research chemicals, pure metals and materials for a wide span of applications. Synthesis and antimicrobial activity of some new quinoxaline derivatives Subba Rami Reddy SR*, Suryanarayana Rao. An efficient and eco-friendly protocol for the synthesis of quinoxaline derivatives employing a condensation reaction between 1,2-diketone and 1,2-diaminobenzene derivative has been developed. In continuation of our study the in vitro antioxidant activity of some novel quinoxaline derivatives was investigated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) method with respect to ascorbic acid. Tetrahedron Lett. A tailor-made medium-band gap fluorinated quinoxaline-based conjugated polymer of PBDT-TFQ was designed and synthesized as a donor material for bulk-heterojunction (BHJ) solar cells. 1 was believed to be a potential template for the synthesis of novel class of bioactive compounds. Chirality-Switchable Catalysts for Asymmetric Synthesis † Particular attention is focused on the exploration of new helical polymer scaffolds that are enantiomercally pure, structurally robust, and readily modifiable at their side chains. a simple and efficient microwave-assisted synthesis of quinoxaline and spiro-indole derivatives in xylene Shivam Bajpai 1 , Sundaram Singh 2 and Vandana srivastava 3 Research Scholar, Department of Chemistry, IIT-BHU, Varanasi, India. Comptes Rendus Chimie - In Press. Efficient syntheses of quinoxalines from the reaction of α-hydroxy ketones and o- phenylenediamine in acetic acid via two methods, a thermal procedure and by microwave irradiation, are described. AI2 was founded to conduct high-impact research and engineering in the field of artificial intelligence. The objective of present research work is to provide green technique for synthesis of quinoxaline derivative. efficient method for the synthesis of quinoxalin-2-ones in up to 86% yield, based on reactions of substituted 2-bromoanilines with pipecolinic acid. Various efficient, mild and eco-friendly methods have been developed for the preparation of quinoxaline derivatives in high yields. Huang et al found Keggin type heteropolyacids to be an efficient and reusable catalyst for the synthesis of biologically active quinoxaline. ir Abstract Efficient syntheses of quinoxalines from the reaction of a-hydroxy ketones and o- phenylenediamine in acetic acid via two methods, a thermal procedure. Efficient synthesis of novel 1,2,3-triazole-linked quinoxaline scaffold via copper-catalyzed click reactions Ali Keivanloo٭a, Mohammad Bakherada, Fateme Abbasia, Tayebeh Besharati-Seidani a, Amir Hossein Amina Characterization data and IR, 1H NMR and 13C NMR spectra of the title compounds: [a] School of Chemistry, Shahrood University of. 2007, 692, 3048-3056. Six new copolymers of 9,9'-dioctylfluorene and 2,3-bis(p-phenylene)quinoxaline were synthesized, characterized, and used as blue-emitting materials in light-emitting diodes (LED. INTRODUCTION:In recent years, the most important goal of synthetic chemists is the development of resource-efficient and sustainable chemical methodologies. In the synthesis, the reaction of 1,2-phenylenediamines and phenacyl bromide were carried out using pyridine as a catalyst in THF at room temperature to give quinoxalines. 3-methyl quinoxaline and 2-methyl-quinoxaline-3yl,5-aryl-2H-tetrazole-2-carboxylate derivatives are synthesized from N'-Arylidene-2-((3-methylquinoxalin-2-yl)oxy) acetohydrazide. AI2 was founded to conduct high-impact research and engineering in the field of artificial intelligence. A highly efficient and facile method has been described for the synthesis of quinoxaline derivatives in good to excellent yields (80-99%) by condensation reaction of heterocyclic as well as aliphatic 1,2-diketones (R 1 COCOR 1, R 1 = Et, Ph, p-MeC 6 H 5, p-MeOC 6 H 5, Furyl) with 1,2-diamines (1,2-(NH 2) 2 C 6 H 3 R 2, R 2 = H, Br, NO 2, PhCO). Supervisor of goals achievement required for projects deadline. An Efficient Protocol for the Synthesis of Quinoxaline Derivatives at Room Temperature Using Recyclable Alumina-Supported Heteropolyoxometalates Diego M. A new efficient route for the formation of quinoxaline N-oxides and N,N'-dioxide using HOF. synthesis of 1,5-benzodiazepine (4) and quinoxaline (5) washed with water (5 mL) and extracted with derivatives, we herein report an expeditious and efficient dichloromethane (10 mL). Both quinoxaline and benzimidazole derivatives are expected to be efficient in cationic photopolymerization with a variety of vinyl and oxide monomers at room temperature upon long wavelength UV irradiation. Quinoxaline derivatives are benzoheterocycles,. Journal of Industrial and Engineering Chemistry. 85 · DOI : 10. Tetrahedron Letters Tetrahedron Letters 46 (2005) 7183-7186 An efficient protocol for the synthesis of quinoxaline derivatives at room temperature using molecular iodine as the catalyst Rajesh S. Chirality-Switchable Catalysts for Asymmetric Synthesis † Particular attention is focused on the exploration of new helical polymer scaffolds that are enantiomercally pure, structurally robust, and readily modifiable at their side chains. , & Wang, Z. Easily synthesized1-methyl-3- (2-oxyethyl) -1H-imidazol-3-ium-borate sulfonic acid {[MOEI] -BSA} as a novel catalyst efficiently promoted the synthesis of quinoxaline derivatives via condensation of various diamines with 1, 2-dicarbonyl compounds at room temperature conditions in ethanol. Ceria and Modified Ceria: A Reusable Catalyst for the Green Synthesis of 2,3-diphenyl Quinoxaline at Room Temperature Simple, highly versatile and efficient synthesis of 2,3-diphenylquinoxalines is achieved from benzil and o-phenylene diamine using ceria and modified ceria as the catalyst. Hence, due to this commendable biological activity the synthesis of some quinoxalines was reported. Tetrahedron Lett. Silica Boron Sulfonic Acid as a New and Efficient Catalyst for the Green Synthesis of Quinoxaline Derivatives at Room Temperature. Quinoxaline derivatives are well known in the pharmaceutical industry and have been shown to possess a broad spectrum of biological activities. An organic electroluminescence device of an embodiment includes a first electrode, a second electrode provided on the first electrode, and a plurality of organic material layers provided between the first electrode and the second electrode, wherein at least one organic material layer among the plurality of organic material layers include a monoamine compound, and the monoamine compound. ir Abstract Efficient syntheses of quinoxalines from the reaction of a-hydroxy ketones and o- phenylenediamine in acetic acid via two methods, a thermal procedure. Supervisor of goals achievement required for projects deadline. Substituted derivatives arise when α-ketonic acids, α-chlorketones, α- aldehyde alcohols and α-ketone alcohols are used in place of diketones. 35 In this article we report the synthesis of quinoxaline derivatives in the presence of IBX. Autino , 1 Nancy Quaranta , 2 Patricia G. The structures of the synthesized compounds were confirmed by 1H NMR, 13C NMR and Mass spectral data. Molecules 2015, 20,. Phytochemical and pharmacological potential of Artemisia absi. Maj, Lionel Delaude, Albert Demonceau, and Alfred F. have investigated the synthesis of quinoxalines in the presence of heteropoly acid at room temperature. Efficient Synthesis of Quinoxaline Derivatives Catalyzed by p-Toluenesulfonic Acid Under Solvent-Free Conditions. Andriamitantsoa, a Jingjing Wang, a Wenjun Dong, a Hongyi Gao, a Ge Wang *a a Beijing Key Laboratory of Function Materials for Molecule & Structure Construction, School.